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N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide

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5.00 tawm ntawm 5 raws li nyob rau 1 neeg ntsuam xyuas
SKU: 681136-29-8. Qeb:

AASraw yog nrog cov khoom siv los ntawm cov grams kom loj hlob ntawm N-phenyl-4- (3-phenyl-1,2,4-thiadiazol-5-yl) piperazine-1-carboxamide hmoov (CAS 681136-29-8), raws li txoj cai CGMP thiab kev tswj xyuas qhov system zoo.

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N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide video


N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide basic Characters

Lub npe: N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide
CAS: 681136-29-8
Purity: ≥99% (HPLC)
txhais: JNJ 1661010;N-Phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1-piperazinecarboxamide;Takeda-25;1-Piperazinecarboxamide, N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-;JNJ 1661010, >=98%
Molecular Formula: C19H19N5OS
Molecular phaus: 365.459
Melting point: 240.48
Kub taw tes: 559.69 ° C ntawm 760 mmHg
ceev: ~ 1.3 g / cm3
Cia Temp: Khw tom + 4 ° C
Dej Cev: DMSO: ≥28mg / mL
Refractive index: n20D 1.68
xim: Crystalline khoom
InChI: InChI=1S/C19H19N5OS/c25-18(20-16-9-5-2-6-10-16)23-11-13-24(14-12-23)19-21-17(22-26-19)15-7-3-1-4-8-15/h1-10H,11-14H2,(H,20,25)
Qhov tseem ceeb hauv InChI: BHBOSTKQCZEAJM-UHFFFAOYSA-N


N-phenyl-4- (3-phenyl-1,2,4-thiadiazol-5-yl) piperazine-1-carboxamid Hmoov siv nyob rau lub voj voog

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N-phenyl-4- (3-phenyl-1,2,4-thiadiazol-5-yl) piperazine-1-carboxamid hmoov, JNJ 166101 hmoov

Ua haujlwm li cas rau N-phenyl-4- (3-phenyl-1,2,4-thiadiazol-5-yl) piperazine-1-carboxamid Hmoov siv

FAAH ua ntej nrog JNJ-1661010 qhia txog kev cuam tshuam kev cuam tshuam ntawm kev sib koom tes ntawm JNJ1661010 thiab thaj chaw ua haujlwm, uas yog ceev dua ntawm qhov kub dua. JNJ-1661010 yog ib qho kev tswj, cov cuab yeej ua haujlwm raws li substrate inhibitor raws li kev soj ntsuam los ntawm LC-ESI-MS. JNJ-1661010 docks nrog lub phenylthiadiazole nyob rau hauv lub qhov dej hydrophobic thiab cov phenylurea hauv hydrophilic hnab tsho ntawm FAAH, JNJ-1661010 (20 mg / kg ip) ua rau FAAH los ntawm tsawg kawg 85% rau 4 h tom qab kev noj tshuaj, ua rau ntawm lub lipid ethanolamides hauv nas lub hlwb. JNJ-1661010 koob tshuaj-rov qab hloov cov tactile allodynia nrog rau ntau tshaj li ntawm 90% ntawm 30 min postdose rau ob qho tib si Nqaij Teeb Nqaij (MTI) nas thiab nas qauv. JNJ-1661010 (20 mg / kg) hloov cov tactile allodynia los ntawm 60.8% ntawm 30 min hauv nas spinal paj hlwb ligation raug mob. JNJ-1661010 (50 mg / kg ip) qhia tau hais tias qhov tseem ceeb ntawm qhov hyperrarthia ntawm 30 min postdose rau hauv cov phom carrageenan tus qauv ntawm qhov mob inflammatory.
Cov nas nyob nrog JNJ-1661010 (20 mg / kg IP) muaj cov ntshav Cmax ntawm 26.9 μM ntawm Tmax ntawm 0.75 h thiab Cmax nyob rau hauv lub hlwb ntawm 6.04 μM ntawm Tmax ntawm 2 h. JNJ-1661010 (20 mg / kg ip) inhibits hlwb FAAH thiab nce qib AEA qib hauv hlwb nqaij hauv nas.

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N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamid Powder

Min yuam 10grams.
Cov lus nug txog ntawm ntau npaum li cas (Hauv 1kg) tuaj yeem xa tawm hauv 12 teev tom qab them nyiaj.
Rau kev loj dua (Hauv 1kg) tuaj yeem xa tawm hauv 3 hnub ua hauj lwm tom qab them nyiaj.

N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamid powder Marketing

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Yuav ua li cas yuav N-phenyl-4- (3-phenyl-1,2,4-thiadiazol-5-yl) piperazine-1-carboxamide hmoov los ntawm AASraw

1.To tiv tauj peb ntawm peb tus email nug qhov system, lossis hauv internettus sawv cev rau tus neeg sawv cev (CSR).
2.To muab peb nug koj qhov ntau thiab qhov chaw nyob.
3.Our CSR yuav muab nqe lus hais txog koj, qhov them nqi, tus lej nrhiav, kev xaib thiab kwv yees hnub uas tuaj txog (ETA).
4.Payment ua tiav thiab cov khoom xa tuaj rau 12 cov xuab moos (Rau kev txiav txim hauv 10kg).
5.Goods tau txais thiab muab tswv yim.

PRECAUTION THIAB DISCLAIMER:

Cov Khoom Siv No Yog Muag Rau Kev Tshawb Xyuas Siv Xwb. Cov ntsiab lus ntawm kev muag khoom Thov. Tsis Yog Rau Tib Neeg Noj, Tsis Kho Mob, Kho Tsiaj, lossis Tsev Neeg Siv.


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N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamid Powder Recipes

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References & cov khoom citations