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Entecavir hydrate hmoov

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5.00 tawm ntawm 5 raws li nyob rau 1 neeg ntsuam xyuas
SKU: 209216-23-9. Qeb:

AASraw yog nrog synthesis thiab muaj peev xwm ua tau los ntawm cov gram rau huab hwm coj ntawm Entecavir hydrate hmoov (209216-23-9), raws li CGMP kev tswj thiab kev tswj cov kev tswj qhov system.

Hauj lwm yam khoom

Entecavir hydrate hmoov video


Raw Entecavir hydrate hmoov theem pib

Lub npe: Entecavir hydrate hmoov
CAS: 209216-23-9
Molecular Formula: C12H17N5O4
Molecular phaus: 295.29
Melt Point: 220-225 ° C
Cia Temp: -20 ° C Freezer
xim: Dawb mus tua dawb Crystalline hmoov


Raw Entecavir hydrate hmoov hauv kev siv

npe

Baraclude

Entecavir hydrate hmoov siv

Entecavir hydrate hmoov yog ib qho muaj zog deoxyguanosine nucleoside analog nrog cov tshuaj tua kab mob rau cov tshuaj hu ua hepatnaviruses (EC50 = 3.7 nM tiv thaiv kab mob siab B (HBV) hauv 2.2.15 daim siab hlwb). Nyob rau hauv vitro, cov dej hauv Entecavir hydrate cov hmoov av, Entecavir hydrate hmoov triphosphate, qhia qhov siab dua rau qhov HBV DNA polymerase dua qhov natural guanosine triphosphate substrate thiab zoo cuam tshuam HBV DNA replication ntawm 3 theem nyob hauv txoj kab rov ua dua: priming, cov khoom sib txuas, thiab DNA DNA nyob ntawm kev sib txuas. Kev siv tshuaj tua hluav taws hauv Entecavir hydrate tau qhia tias muaj cov ntoo thiab cov qauv kab mob HBV. Cov dej num tau pom zoo hauv theem I / II kev tshawb fawb thiab Entecavir hydrate hmoov tau txais kev pom zoo los ntawm US Food and Drug Administration rau kev kho mob ntawm cov laus uas muaj kab mob siab B ntev.

Entecavir hydrate nyoos hmoov (ETV), muag raws li lub npe Tshuaj Baraclude, yog tshuaj antiviral uas siv los kho tus kab mob siab B (HBV). Cov neeg mob HIV / AIDS thiab HBV antiretroviral tshuaj yuav tsum tau siv. Entecavir hydrate hmoov yog coj los ntawm qhov ncauj ua ib ntsiav tshuaj los yog kua.

Cov kev mob tshwm sim muaj xws li mob taub hau, xeev siab, ntshav qab zib siab, thiab tsis ua hauj lwm hauv lub raum. Cov kev phiv loj heev muaj xws li kev loj hlob ntawm daim siab, ntshav siab lactate, thiab daim siab mob yog tias cov tshuaj nres. Txawm hais tias tsis zoo los ntawm kev siv thaum cev xeeb tub, qhov kev siv no tsis tau kawm zoo. Entecavir hydrate nyoos hmoov yog nyob hauv cov nucleoside thim rov qab transcriptase (NRTIs) tsev neeg cov tshuaj. Nws txwv tsis pub tus kabmob siab B tawm ntawm kev sib kis los ntawm thaiv kev thim rov qab transcriptase.

Entecavir hydrate hmoov yog siv los kho tus kab mob siab hepatitis B rau cov neeg laus thiab cov menyuam yaus 2 xyoo thiab laus dua nrog cov kab mob viral replication thiab cov pov thawj ntawm tus kab mob uas muaj kab mob hauv siab nrog cov kev siab ntawm daim siab enzymes. Nws kuj yog siv los tiv thaiv HBV reinfection tom qab hloov daim siab thiab kho cov neeg mob HIV mob HBV. Entecavir hydrate raw khoom tiv thaiv kab mob HIV, tab sis tsis pom zoo siv rau cov neeg mob HIV-HBV cov kab mob uas tsis muaj kev tswj fwm tshuaj tiv thaiv kab mob HIV [9] raws li nws muaj peev xwm xaiv tau los tiv thaiv lamivudine thiab emtricitabine hauv HIV.

Kev ua hauj lwm ntawm Entecavir hydrate hmoov tau kawm nyob rau hauv ob peb randomized, ob-dig muag, ntau zaus sim. Entecavir hydrate hmoov los ntawm lub qhov ncauj yog siv tau thiab kev kho mob feem ntau zoo.

Entecavir hydrate nyoos hmoov yog coj los ntawm qhov ncauj ua ib ntsiav tshuaj los yog kua. Cov tshuaj raws li tus neeg qhov hnyav. Cov tshuaj yog pom zoo rau cov me nyuam ntau dua 2 xyoo uas hnyav txog 30 kg. Entecavir hydrate hmoov yog kev pom zoo rau ntawm lub plab uas khoob me me tsawg kawg ntawm 2 ua ntej los yog tom qab noj mov, feem ntau tib lub sijhawm txhua txhua hnub. Nws tsis yog siv rau hauv cov me nyuam tsawg dua 2 xyoo. Cov kev kho kom haum mas kuj pom zoo rau cov neeg uas tsis tshua muaj raum ua haujlwm.

Ceeb toom rau Entecavir hydrate hmoov

Feem ntau ntawm cov neeg uas siv Entecavir hydrate hmoov muaj tsawg los tsis muaj kev phiv. Cov kev mob tshwm sim feem ntau muaj xws li mob taub hau, nkees, kiv taub hau, thiab xeev siab. Tsawg tshaj qhov tshwm sim muaj xws li teeb meem pw tsaug zog thiab kev mob plab hnyuv ntxwm xws li kua qaub, plab, thiab ntuav.

Kev mob loj los ntawm Entecavir hydrate raw hmoov muaj xws li lactic acidosis, teeb meem rau daim siab, mob siab, thiab muaj roj nyob hauv siab.

Cov kev kuaj mob hauv tsev kuaj pom tau pom tias muaj tus kabmob txiav (Alanine transaminase) (ALT), hematuria, glycosuria, thiab nce hauv lipase. Ntsuas saib xyuas cov kev ua haujlwm thiab hom kab mob hematology raug pom zoo.

Cov lus qhia ntxiv

Entecavir hydrate hmoov yog ib qho hluavtaws analog 2-deoxyguanosine nrog kev tiv thaiv kab mob siab tiv thaiv kab mob siab B (HBV). Entecavir hydrate nyoos hmoov pauv mus rau hauv vivo rau 5-triphosphate metabolite. Lawm, daim ntawv thaij daim ntawv sib tw nrog sib tw nrog lub natural substrate deoxyguanosine triphosphate (dGTP) rau kev nkag mus rau hauv cov kab DNA. Lub koom tes ntawm cov activated triphosphate metabolite ntawm Entecavir hydrate hmoov inhibits tus nraub qaum transcriptase (RT) viral RNA-dependent HBV DNA polymerase thiab, yog li, cov replication ntawm kab DNA thiab transcription.

Entecavir hydrate raw hmoov yog ib guanosine nucleoside analogue siv los kho tus kab mob siab B mob siab (HBV). Entecavir hydrate hmoov tshuaj tuaj yeem txuam nrog cov kab mob siab B lub cev thaum los yog tom qab kho, tiam sis tsis tau txuas rau cov neeg mob uas pom kev mob siab.

Entecavir hydrate Raw Powder

Min yuam 10grams.
Cov lus nug txog ntawm ntau npaum li cas (Hauv 1kg) tuaj yeem xa tawm hauv 12 teev tom qab them nyiaj.
Rau kev loj dua (Hauv 1kg) tuaj yeem xa tawm hauv 3 hnub ua hauj lwm tom qab them nyiaj.

Entecavir hydrate hmoov muag

Kom muab rau yav tom ntej tom ntej.


Yuav ua li cas yuav Entecavir hydrate hmoov los ntawm AASraw

1.To tiv tauj peb ntawm peb tus email nug qhov system, lossis hauv internettus sawv cev rau tus neeg sawv cev (CSR).
2.To muab peb nug koj qhov ntau thiab qhov chaw nyob.
3.Our CSR yuav muab nqe lus hais txog koj, qhov them nqi, tus lej nrhiav, kev xaib thiab kwv yees hnub uas tuaj txog (ETA).
4.Payment ua tiav thiab cov khoom xa tuaj rau 12 cov xuab moos (Rau kev txiav txim hauv 10kg).
5.Goods tau txais thiab muab tswv yim.

PRECAUTION THIAB DISCLAIMER:

Cov Khoom Siv No Yog Muag Rau Kev Tshawb Xyuas Siv Xwb. Cov ntsiab lus ntawm kev muag khoom Thov. Tsis Yog Rau Tib Neeg Noj, Tsis Kho Mob, Kho Tsiaj, lossis Tsev Neeg Siv.


COA

HNMR

Entecavir hydrate hmoov (209216-23-9) ≥98% | AASraw R & D Reagents

Zaub mov txawv

Entecavir hydrate Nqaij Khoom Noj Hmoov Noj:

Yog xav paub txog peb Tus Neeg Sawv Cev Kev Nkag Siab (CSR) kom paub meej, rau qhov koj siv.

References & cov khoom citations

9 yam txog Entecavir hydrate