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Hydroxyprogesterone caproate hmoov

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5.00 tawm ntawm 5 raws li nyob rau 1 neeg ntsuam xyuas
SKU: 630-56-8. Qeb:

AASraw yog nrog synthesis thiab muaj peev xwm ua tau los ntawm cov gram kom huab hwm coj ntawm Hydroxyprogesterone caproate hmoov (630-56-8), raws li CGMP kev tswj thiab kev tswj xyuas qhov system.

Hydroxyprogesterone caproate hmoov yog ib qho khoom sib hlab nqus cov kab mob uas zoo sib xws rau medroxyprogesterone acetate thiab megestrol acetate. Nws yog ib qho ester derivative ntawm 17α-hydroxyprogesterone ua los ntawm caproic acid (hexanoic acid). Hydroxyprogesterone caproate yog yav tas los hauv kev lag luam hauv lub npe MAKENA.

Hauj lwm yam khoom

Hydroxyprogesterone caproate hmoov video


Hydroxyprogesterone caproate hmoov theem pib

Lub npe: Hydroxyprogesterone caproate hmoov
CAS: 630-56-8
Molecular Formula: C27H40O4
Molecular phaus: 428.6
Melt Point: 120 ° -124 ° C
Cia Temp: RT
xim: Dawb hmoov


Hydroxyprogesterone caproate hmoov

npe

Cov npe tshuaj: Hydroxyprogesterone caproate hmoov
Hom Npe: Hydroxyprogesterone caproate (OHPC) hmoov, Delalutin hmoov, Proluton hmoov, 630-56-8

Hydroxyprogesterone caproate hmoov siv

COV LUS QHIA NO YOG RAU COV NEEG TSO NPE THOV NTSUAB XWB THIAB TSIS TXHOB SIV LOS YOG TUS NEEG SIV RAU KEV QHIA LOSSIS LWM TUS KHO TSHUAJ TIV THAIV KAB MOB.

1) Rau preterm yug prophylaxis rau cov maum nrog ib tus poj niam cev xeeb tub uas muaj keeb kwm ntawm singleton spontaneous preterm yug.

Cov hnoos qog intramuscular (tib qho thiab ntau koob tshuaj vials Makena xwb)
Cov laus thiab cov tub ntxhais hluas cov poj niam cev xeeb tub 16 xyoo thiab laus dua
250 mg (1 mL) IM zaug ib zaug (txhua txhua hnub 7). Pib kho txhua lub sijhawm ntawm 16 lub lis piam thiab 0 hnub ntawm cev xeeb tub txog 20 lub lis piam thiab 6 hnub ntawm cev xeeb tub. Mus txuas ntxiv ib lim tiam kom txog thaum lub lim tiam 37 (los ntawm 36 lub lis piam, 6 hnub) ntawm kev ua niam txiv lossis tus me nyuam, seb qhov twg tshwm sim ua ntej. Kev ua hauj lwm zoo ntawm hydroxyprogesterone yog los ntawm kev txhim kho nyob rau hauv qhov kev faib ua feem ntawm cov poj niam uas tau xa los ntawm tsawg dua 37 lub lis piam gestation. Kuj tsis muaj kev sim tswj kev sib tw uas qhia tau cov txiaj ntsim kev pab ncaj qha, xws li kev txhim kho hauv lub cev tuag thiab kev mob morbidity. Kev txwv ntawm kev siv: Hydroxyprogesterone tsis yog siv rau kev siv rau cov poj niam uas muaj ntau yam gestations lossis lwm yam kev pheej hmoo yam yuav tsum tau ua ntej yug menyuam.

Subcutaneous koob (Makena pib-injector nkaus xwb)
Cov laus thiab cov tub ntxhais hluas cov poj niam cev xeeb tub 16 xyoo thiab laus dua
275 mg (1.1 mL) subcutaneously ib lim piam ib zaug (txhua hnub 7). Pib kho txhua lub sijhawm ntawm 16 lub lis piam thiab 0 hnub ntawm cev xeeb tub txog 20 lub lis piam thiab 6 hnub ntawm cev xeeb tub. Mus txuas ntxiv ib lim tiam kom txog thaum lub lim tiam 37 (los ntawm 36 lub lis piam, 6 hnub) ntawm kev ua niam txiv lossis tus me nyuam, seb qhov twg tshwm sim ua ntej. Kev ua hauj lwm zoo ntawm hydroxyprogesterone yog los ntawm kev txhim kho nyob rau hauv qhov kev faib ua feem ntawm cov poj niam uas tau xa los ntawm tsawg dua 37 lub lis piam gestation. Kuj tsis muaj kev sim tswj kev sib tw uas qhia tau cov txiaj ntsim kev pab ncaj qha, xws li kev txhim kho hauv lub cev tuag thiab kev mob morbidity. Kev txwv ntawm kev siv: Hydroxyprogesterone tsis yog siv rau kev siv rau cov poj niam uas muaj ntau yam gestations lossis lwm yam kev pheej hmoo yam yuav tsum tau ua ntej yug menyuam.

2) Rau kev kho mob ntawm cov kab mob ua tsis taus hauj lwm, rov muaj dua, thiab kev tiv thaiv kabmob (metastatic endometrial).

Cov hnoos qeev intramuscular
Cov poj niam laus
1,000 mg los yog ntau dua ib lub lim piam IM (ntau 1 gram IM zaug ib lim piam twg rau 1 grams IM ib zaug ib hnub). Tshem tawm thaum rov qab kis, los sis tom qab 12 lub lis piam tsis muaj lub hom phiaj teb. Tej zaum yuav raug siv nyob rau hauv qib siab sib luag nrog lwm qhov kev kho mob anticancer (kev phais mob, hluav taws xob, los yog cov kws khomob, lossis ua ke ntawm cov no). Cov txiaj ntsim kev kho mob tau qhia txog hnub tau zoo dua nyob rau hauv cov keeb kwm zoo ntawm cov keeb kwm ntawm endometrial adenocarcinoma.

3) Kev kho mob ntawm amenorrhea (thawj los yog theem nrab) los yog kev ua haujlwm tsis haum los ntawm kev tsis tuaj yeem los ntawm hormonal tsis txaus los ntawm qhov tsis muaj organic pathology.

Cov hnoos qeev intramuscular
Cov poj niam thiab cov ntxhais hluas
375 mg IM yog ib koob, muab lub sijhawm twg los tau. Cov koob tshuaj tom ntej no yuav pib tom qab 4 hnub ntawm kev ua los yog, yog tias tsis muaj los ntshav, 21 hnub tom qab thawj zaug ib zaug. Yog hais tias tsis muaj lus teb tom qab 4 mus, txiav lawm. Tus naj npawb ntawm kev siv thiab thaum twg siv cyclic dosing yog nyob ntawm seb qhov kev siv thiab seb tshuaj estrogen yog siv sib luag. Ib lub tswv yim cyclic nrog cov tshuaj no yog raws li nram no (28-hnub voj voog, rov txhua txhua lub lim tiam 4) Hnub 1 ntawm txhua lub voj voog: Estradiol Valerate Txhaj (20 mg IM); ces, 2 lub lis piam tom qab Hnub 1: Hydroxyprogesterone caproate hmoov 250 mg IM; ces Estradiol Valerate (5 mg IM) 4 lub lis piam tom qab Hnub 1: Qhov no yog Hnub 1 ntawm cov kab ke tom ntej. Rov hais dua. Yog tias estrogen deficiency tau ntev lawm rau cov neeg mob uas muaj amenorrhea, cov pojniam yuav tsis tuaj yeem tshwm sim kom txog thaum tshuaj estrogen tau ntau lub hlis. Tshem tawm thaum cyclic kho tsis tau lawm.
Txheeb tshuaj rau cov tshuaj estrogen endogenous ("Medical D thiab C").
Cov hnoos qeev intramuscular
Cov poj niam laus
250 mg IM zaug ib zaug; rov ua dua rau kev pom zoo tom 4 lub lis piam tom qab thawj zaug txhaj tshuaj. Tshem tawm tom qab koob thib ob. Ntshav yuav tsum tshwm sim 7 rau 14 hnub tom qab txhaj tshuaj.

Ceeb toom rau Hydroxyprogesterone caproate hmoov

Hydroxyprogesterone caproate hmoov tshuaj txhaj tshuaj, nrog rau cov tshuaj compounded, ua tau raws li qhov kev siv tshuaj kho mob thaum siv los txo qhov kev pheej hmoo ntawm kev yug menyuam hauv cov poj niam thiab tag nrho cov kev ntsuas nram no:

1. Tus tswv cuab muaj ib tus pojniam cev xeeb tub tam sim no.
2. Tus tswv cuab muaj daim ntawv teev cov menyuam yaus ua ntej yug tus pojniam uas tau tshwm sim tsawg dua 37 lub lis piam gestation vim yog kev mob nkeeg lossis kev tuaj yeem ntxov ntawm lub cev.
3. Tus tswvcuab tsis tau muaj menyuam yaus ua haujlwm lossis ua haujlwm thaum ntxov hauv plab tam sim no.
4. Kev kho yog pib ntawm 16 lub lis piam, 0 hnub thiab 20 lub lis piam, 6 hnub ntawm gestation.
5. Cov tshuaj tsis yog yuav tsum tau txhaj ntau zaus ntau dua txhua lub lim tiam kom txog thaum 36 lub lis piam gestation los yog lub sijhawm yug (qhov twg tshwm sim ua ntej) rau ntau tshaj tsis pub tshaj 21 cov tshuaj.
6. Dose tsis tshaj 250 mg ib zaug txhaj tshuaj.

Cov lus qhia ntxiv

Cov npe tshuaj Hydroxyprogesterone caproate hmoov yog lub cev xeeb tub-4-en-3,20-dione, 17 [(1oxohexyl) oxy]. Nws muaj ib qho xim ntawm C27H40O4 thiab lub cev ntawm 428.60 molecular. Hydroxyprogesterone caproate hmoov tshwm sim li dawb dawb rau cov pob zeb dawb los yog cov hmoov uas muaj lub ntsiab lus ntawm 120 °-124 ° C.

Hydroxyprogesterone caproate hmoov mechanism ntawm kev txiav txim: qhov kev siv los ntawm progesterone tiv thaiv preterm yug tsis zoo, tab sis muaj ntau txoj hauv kev yuav koom tes nrog.Progesterone plays lub luag hauj lwm tseem ceeb ntawm cov poj niam deev thiab nws tseem ceeb heev rau kev txhim kho implantation ntawm lub embryo thiab kev kho ntawm cev xeeb tub. Nws ua los ntawm kev khi rau progesterone receptors nyob rau hauv tsev menyuam, zes qe menyuam, cov mis thiab nyob rau hauv lub hauv nruab nrab lub paj hlwb. Cov neeg txais kev pom zoo muaj nyob hauv 2 isoforms, PR-A thiab PR-B. Progesterone khi rau cov receptors thaum kawg ua rau kev tswj cov noob transcription.Qhov no tau tshwm sim los ntawm cov tshuaj tua kab mob uas cuam tshuam rau lub xeev proinflammatory uas pib nrog kev pib ua haujlwm, thiab tswj lub uterine queiscence los ntawm stabilizing progesterone ua rau ntawm qhov kev ntsuas hauv lub plawv.

Pharmacodynamics ntawm Hydroxyprogesterone caproate hmoov: Tsis muaj kev tshawb fawb tshuaj pharmacodynamic tau ua kom ntsuam xyuas Hydroxyprogesterone caproate hmoov tov tshuaj. Txawm li cas los xij, qhov kev nqis tes ua los ntawm kev nqis tes ua yuav muaj feem cuam tshuam nrog kev nce qib ntawm progesterone thiab progesterone receptors.

Hydroxyprogesterone caproate hmoov ib nrab neej yog 16 hnub (± 6 hnub).

Hydroxyprogesterone caproate hmoov Raw hmoov

Min yuam 10grams.
Cov lus nug txog ntawm ntau npaum li cas (Hauv 1kg) tuaj yeem xa tawm hauv 12 teev tom qab them nyiaj.
Rau kev loj dua (Hauv 1kg) tuaj yeem xa tawm hauv 3 hnub ua hauj lwm tom qab them nyiaj.

Hydroxyprogesterone caproate hmoov li

Kom muab rau yav tom ntej tom ntej.


Yuav ua li cas yuav Hydroxyprogesterone caproate hmoov los ntawm AASraw

1.To tiv tauj peb ntawm peb tus email nug qhov system, lossis hauv internettus sawv cev rau tus neeg sawv cev (CSR).
2.To muab peb nug koj qhov ntau thiab qhov chaw nyob.
3.Our CSR yuav muab nqe lus hais txog koj, qhov them nqi, tus lej nrhiav, kev xaib thiab kwv yees hnub uas tuaj txog (ETA).
4.Payment ua tiav thiab cov khoom xa tuaj rau 12 cov xuab moos (Rau kev txiav txim hauv 10kg).
5.Goods tau txais thiab muab tswv yim.

PRECAUTION THIAB DISCLAIMER:

Cov Khoom Siv No Yog Muag Rau Kev Tshawb Xyuas Siv Xwb. Cov ntsiab lus ntawm kev muag khoom Thov. Tsis Yog Rau Tib Neeg Noj, Tsis Kho Mob, Kho Tsiaj, lossis Tsev Neeg Siv.


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COA

COA 630-56-8 Hydroxyprogesterone caproate hmoov AASRAW

HNMR

630-56-8 Hydroxyprogesterone caproate AASRAW HMNR

Zaub mov txawv

References & cov khoom citations