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Lapatinib hmoov (231277-92-2)

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5.00 tawm ntawm 5 raws li nyob rau 1 neeg ntsuam xyuas
SKU: 231277-92-2. Qeb:

AASraw yog nrog synthesis thiab muaj peev xwm ua tau los ntawm cov gram kom huab hwm coj ntawm Lapatinib hmoov (231277-92-2), raws li CGMP kev tswj thiab kev tswj xyuas qhov system.

Hauj lwm yam khoom

Lapatinib hmoov video


Lapatinib hmoov theem pib

Lub npe: Lapatinib hmoov
CAS: 231277-92-2
Molecular Formula: C29H26ClFN4O4S
Molecular phaus: 581.05
Melt Point: 136-140 ° C
Cia Temp: tub yees
xim: Dawb los yog tua dawb Crystalline hmoov


Raw Lapatinib hmoov hauv cov kab mob Antineoplastic

npe

Generic Name: Lapatinib hmoov (la paj tin ib)
Hom Lub Npe: Tykerb

Raw Lapatinib Hmoov Pab

Lapatinib hmoov yog ib hom tshuaj siv nrog lwm cov tshuaj (capcitabine) los kho cov neeg muaj mob cancer mis uas tau kis mus rau lwm qhov chaw hauv HER2 positive (cov hlav uas ua rau ntau cov protein uas hu ua epidermal growth factor receptor-2) , thiab leej twg twb muaj lwm cov kev kho mob cancer mis.

Lapatinib hmoov kuj siv nrog hom tshuaj hu ua letrozole rau kev kho mob postmenopausal poj niam nrog hormone receptor zoo, HER2 zoo metastatic mis mob cancer rau leej twg hormonal therapy yog qhia.

Lapatinib hmoov yog ib hom tshuaj siv los kho mob cancer mis. Nws siv nrog lwm cov tshuaj los kho ib hom qog nqaij hlav cancer mis uas tau kis mus rau lwm qhov hauv lub cev thiab tsis tau txais kev kho mob lwm yam kabmob kheesxaws.

Lapatinib hmoov yog rau ib pawg ntawm cov tshuaj hu ua kinase inhibitors uas ua haujlwm los ntawm kev thaiv qhov kev txiav txim ntawm ib qho protein ntau uas qhia cov kabmob kheesxaws kuaj kabmob.

Cov tshuaj no tuaj rau ntawm daim ntawv xaj thiab noj ib hnub ib zaug rau ntawm lub plab.

Cov kev mob tshwm sim ntawm Lapatinib hmoov muaj xws li liab, mob tes thiab taw, raws plab, pob khaus, thiab xeev siab.

Qhov ntau npaum li cas ntawm Lapatinib hmoov

Tus Kab Mob Qis Qis Qis rau Tus Neeg Mob Cancer Mis

-HER2-POSITIVE METASTATIC BREAST CANCER (nrog rau capecitabine): 1250 mg lus ib zaug ib hnub twg ntawm Hnub 1 rau 21 tas li ntawm 21-hnub mus kom txog thaum muaj kab mob los yog tsis kis tau tus mob toxicity.

-HORMONE RECEPTOR-POSITIVE, HER2-POSITIVE METASTATIC BREAST CANCER (nrog rau cov tshuaj hurozole): 1500 mg lus ib zaug ib hnub ib zaug.

Comments:
-Consult cov ntaub ntawv tsim khoom siv rau cov capecitabine thiab cov tshuaj pomoczole dosing.
-HER2-zoo metastatic mis mob cancer cov neeg mob yuav tsum muaj tus kab mob ntawm kev mob trastuzumab ua ntej pib kev kho mob nrog cov tshuaj no nrog rau cov capecitabine.

Siv:
-Ua nruab nrog capecitabine rau kev kho mob ntawm cov neeg mob uas mob siab lossis mob metastatic lub mis cancer uas nws cov hlav overexpress HER2 thiab leej twg tau txais kev kho mob ua ntej nrog rau anthracycline, taxane, thiab trastuzumab.
-Nyob rau hauv kev ua ke nrog rau cov kev kho mob postmenopausal cov poj niam uas muaj cov tshuaj hormone receptor metastatic lub mis mob cancer uas overexpresses tus HER2 tus neeg tuaj yeem rau tus neeg hormonal therapy yog qhia.

Kev Hloov Dab Tsi Ua Ntej
Cov ntaub ntawv tsis muaj hais txog kev hloov kho ntau npaum li cas; li cas los xij, cov pharmacokinetics ntawm cov tshuaj no tsis tshua muaj kev cuam tshuam los ntawm qhov tsawg tshaj li 2% ntawm kev txhaj tshuaj yog tshem tawm los ntawm ob lub raum.

Mob Siab Dose Kev Hloov
PRE-TUS ME NYUAM RAU HOM ​​TSHUAJ TIV THAIV KAB MOB (TSHUAJ-PUGH A / B): Cov ntaub ntawv tsis muaj.

TSHUAJ TIV THAIV KOM ZOO HEEV TSHUAJ TIV THAIV (TUS ME NYUAM PUV C): Txo kev noj tshuaj:
-HER2-Positive Metastatic Breast Cancer (nrog rau cov capecitabine): 750 mg / hnub.
-Hormone Receptor-Positive, HER2-Zoo Mob Cancer Mis (nrog rau cov tshuaj hurozole): 1000 mg / hnub

SAB HAIS TXOG HEPATOTOXICITY OCCURS THERAPY: Ntev tsis tuaj yeem kho.

Comments: Cov kev kho tawm tswv yim pom zoo yog raws li cov kev tshawb fawb ntawm pharmacokinetic; tsis muaj cov ntaub ntawv kuaj mob muaj.

Cov Kev Kho Dose
TSIS TXAUS SIV NROG ZOG CYP450 3A4 INHIBITORS THIAB / LOS SIS TSIS TXAUS SIV XYUAS XYUMXXXUMX INDUCERS: Tsis txhob siv yog tias ua tau. Kev kho cov kev xav kom haum yog ua raws li cov kev tshawb fawb ntawm pharmacokinetic; tsis muaj cov ntaub ntawv kuaj mob muaj.
TSIS TXAUS SIV NROG ZOG CYP450 3A4 INHIBITOR: Txo cov koob tshuaj rau 500 mg / hnub; tso cai rau lub sijhawm ua haujlwm txog 1 lub sijhawm ua ntej yuav hloov kho ntawm cov tshuaj no mus rau cov tshuaj uas niaj zaus siv yog tias inhibitor tsis ua haujlwm.
TSIS TXAUS SIV NROG QIV KHOOM CYP450 3A4 INDUCER: Maj mam nce raws cov tshuaj tiv thaiv; txo cov koob tshuaj rov qab kom rov qab txhaj tshuaj yog tias inducer sis txiav.
-HER2-Positive Metastatic Breast Cancer (nrog rau capecitabine): Ua kom koob ntxiv mus txog 4500 mg / hnub.
Hormone Receptor-Positive, HER2-Positive Metastatic Breast Cancer (nrog rau cov tshuaj hurozole): Ua kom koob ntxiv mus txog 5500 mg / hnub.

QIB 2 LOSSIS LOSSIS LOS YOG LEEJ TWG TXOJ KEV TXUAS LOS NTAWM LOSSIS LOSSIS LOVE LOSTAWV UAS TSIM NYOG RAWS LI HAIS TXOG COV TSWV NTAWM NORMAL: Tshem tawm kev kho mob; yuav pib rov qab txo cov tshuaj tom qab tsawg kawg ntawm 2 lub lim piam yog tias LVEF rov qab zoo dua qub thiab tus neeg mob yog asymptomatic.
Txo Cov Cai Txo:
-HER2-Positive Metastatic Breast Cancer (nrog rau capecitabine): 1000 mg / hnub
-Hormone Receptor-Positive, HER2-Zoo Mob Cancer Mis (nrog rau cov tshuaj hurozole): 1250 mg / hnub

QIB 3 LOS SIS 1 los yog 2 DIARRHEA NROG KOM ZOO NTXIV (ploj los sis mob plab mob dua, Qib 2 lossis ntau dua xeev siab los yog ntuav, ua tsis tau zoo, ua npaws, sepsis, neutropenia, ntshav los ntshav, los yog lub cev qhuav dej) txhawm rau qib 1 los yog tsawg dua.
Txo Cov Cai Txo:
-HER2-Kom Positive Metastatic Cancer Mis (nrog rau cov capecitabine): 1000 mg / hnub
-Hormone Receptor-Kom Zoo, HER2-Kom Positive Metastatic Cancer Cov neeg mob: 1250mg / hnub
QIB 4 DIARRHEA: Txiav kev mus tas li.

LWM COV HAIV NEEG, QIB XYUMX lossis HWJ SIAB: Tej zaum yuav xav tias yuav tsum tsis ua ntxiv lawm los sis txiav tu ncua; yuav rov qab pib ntawm qhov tshuaj uas tau pom zoo li qub thaum toxicity pab rau Qib 2 los yog tsawg dua.
YOG HAIV NEEG TSWV YIM TSIS TAU: Txo kev noj tshuaj:
-HER2-Positive Metastatic Breast Cancer (nrog rau capecitabine): 1000 mg / hnub
-Hormone Receptor-Kom Zoo, HER2-Kom Positive Metastatic Cancer Cov neeg mob: 1250mg / hnub

Ua li cas raw Lapatinib hmoov ua haujlwm

Lapatinib hmoov yog siv nrog capecitabine (Xeloda) los kho ib hom kev mob khees xaws mis ntxiv rau cov neeg uas tau raug kho nrog lwm cov tshuaj tua kab mob. Lapatinib hmoov yog nyob hauv chav kawm ntawm cov tshuaj hu ua kinase inhibitors. Nws ua haujlwm los ntawm kev thaiv qhov kev txiav txim ntawm qhov txawv txav ntawm cov hlab ntsha uas ua rau mob qog hlwb. Qhov no pab nres lossis qeeb kis qog hlwb.

Ceeb toom

Qhia tag nrho koj cov kws kho mob uas koj noj Lapatinib hmoov. Qhov no suav nrog koj cov kws kho mob, cov kws saib mob, cov kws tshuaj, thiab cov kws kho hniav.
Yog tias koj muaj mob plab, ntuav, quav quav (plab), lossis tsis tshaib plab, nrog koj tus kws kho mob tham. Tej zaum yuav muaj kev txo qis cov kev mob tshwm sim.
Quav quav (plab) tau tshwm sim nrog Lapatinib hmoov. Qee zaum, kev zawv plab tau ua phem heev thiab tuag tau tshwm sim. Nrog koj tus kws kho mob tham.
Yog tias koj muaj quav quav (mob raws plab), nrog koj tus kws kho mob tham. Tsis txhob sim ua kom raws plab yam tsis tau kuaj thawj zaug nrog koj tus kws kho mob.
Ntsuas ntshav kuaj xyuas thaum koj tus kws kho mob tau qhia rau koj. Tham nrog tus kws kho mob.
Koj yuav tsum muaj kev ntsuam xyuas lub plawv thaum koj noj Lapatinib hmoov. Tham nrog tus kws kho mob.
Tsis txhob muaj cov txiv lws zoov thiab kua txiv lws txiv hmab txiv ntoo.
Yog tias koj noj digoxin, nrog koj tus kws kho mob tham. Tej zaum koj yuav tau kuaj koj cov ntshav ua kom zoo dua thaum koj noj nrog Lapatinib hmoov.
Cov tshuaj no yuav tsim teebmeem rau tus menyuam hauv plab yog tias koj noj thaum koj xeeb tub.
Siv kev tswj kom tsis txhob muaj menyuam yaus uas koj tuaj yeem ntseeg kom tsis txhob muaj menyuam hauv plab thaum noj Lapatinib hmoov.
Yog tias koj cev xeeb tub los yog koj xeeb tub thaum koj noj Lapatinib hmoov, hu rau koj tus kws kho mob kom yog.

Lapatinib Raw Hmoov

Min yuam 10grams.
Cov lus nug txog ntawm ntau npaum li cas (Hauv 1kg) tuaj yeem xa tawm hauv 12 teev tom qab them nyiaj.
Kev txiav txim loj dua tuaj yeem xa tawm hauv 3 hnub ua hauj lwm tom qab them nqi.

Lapatinib hmoov muag

Kom muab rau yav tom ntej tom ntej.

Yog Lapatinib cov hmoov tsis muaj lwm yam mob

Nrog rau nws cov teebmeem uas tsim nyog, Lapatinib hmoov yuav ua rau muaj qee yam tsis txaus siab. Txawm tias tag nrho cov kev mob tshwm sim no yuav tshwm sim, yog tias lawv tshwm sim lawv xav tau kev kho mob.

Kuaj nrog koj tus kws kho mob tam sim ntawd yog tias muaj tej yam tshwm sim nram no thaum noj cov tshuaj Lapatinib:

Tsawg dua
Nyuaj los yog ua haujlwm ua haujlwm
tsaus muag
lub plawv dhia ceev ceev los yog tsis zoo
mob plab heev
ceev ceev hauv siab
qaug zog lossis tsis muaj zog
Tsis tshua muaj

Mob plab lossis mob plab lossis mob plab
av nplaum quav
tsaus zis
tsis qab los noj mov
ua npaws
mob taub hau
khaus lossis tawv nqaij pob
tsis qab los noj mov
xeev siab thiab ntuav
o ntawm taw los yog sab ceg
qhov muag daj lossis tawv nqaij
Cov xwm txheej tsis paub
Hlwv, chwv, xoos ntawm daim tawv nqaij
mob hauv siab
tshee
hnoos
raws plab
nyuaj nrog nqos
kiv taub hau
kev xav tsis zoo los yog mob
khaus
mob leeg lossis mob leeg
puffiness lossis o ntawm ob lub qhov muag lossis qhov muag, ntsej muag, di ncauj, lossis nplaig
liab tawv nqaij txhab ntshav, feem ntau nrog lub plawv ntshav
liab, khaus qhov muag
mob caj pas
qhov nqaij, qhov mob, los yog cov pob dawb dawb ntawm qhov ncauj lossis ntawm daim di ncauj
thickening ntawm bronchial secretions
Qee cov kev mob ntawm Lapatinib hmoov tuaj yeem tshwm sim uas feem ntau tsis xav tau kev kho mob. Cov kev mob tshwm sim no yuav ploj mus thaum kho thaum koj lub cev nyob rau hauv cov tshuaj. Tsis tas li ntawd, koj tus kws kho mob yuav tuaj yeem qhia koj txog kev tiv thaiv los yog txo qee qhov kev mob tshwm sim. Nrog koj tus kws kho mob tham yog tias ib qho ntawm cov kev mob tshwm sim tom ntej los yog muaj kev ntxhov siab lossis koj muaj lus nug txog lawv:

Ntau hom
Acid los yog qaub lub plab
rov qab mob
belching
tawg di ncauj
zawv plab (me me)
qhuav tawv nqaij
kub siab
kem plab
mob hauv caj npab los yog txhais ceg
liab, o, los yog mob tawv nqaij
txhuam ntawm daim tawv nqaij ntawm tes thiab taw
qhov nqaij, qhov mob, los yog cov pob dawb dawb ntawm daim di ncauj, tus nplaig, los yog hauv lub qhov ncauj
lub plab tsis xis nyob, chim, lossis mob
o los yog o ntawm lub qhov ncauj
tingling ntawm txhais tes thiab taw
teeb meem pw tsaug zog


Yuav ua li cas yuav Lapatinib hmoov los ntawm AASraw

1.To tiv tauj peb ntawm peb tus email nug qhov system, lossis hauv internettus sawv cev rau tus neeg sawv cev (CSR).
2.To muab peb nug koj qhov ntau thiab qhov chaw nyob.
3.Our CSR yuav muab nqe lus hais txog koj, qhov them nqi, tus lej nrhiav, kev xaib thiab kwv yees hnub uas tuaj txog (ETA).
4.Payment ua tiav thiab cov khoom xa tuaj rau 12 cov xuab moos (Rau kev txiav txim hauv 10kg).
5.Goods tau txais thiab muab tswv yim.


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COA

COA 231277-92-2 Lapatinib hmoov AASRAW

HNMR

Peb yog Lapatinib hmoov supplie, Lapatinib hmoov muag, Raw Lapatinib hmoov (231277-92-2) hplc = 98% | AASraw R & D Reagents

Zaub mov txawv

Lapatinib Raw Pluas Noj Zaub:

Yog xav paub txog peb Tus Neeg Sawv Cev Kev Nkag Siab (CSR) kom paub meej, rau qhov koj siv.

References & cov khoom citations

Tykerb (231277-92-2) - Lub taub hau ntawm lub mis nyuj