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Levonorgestrel hmoov

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5.00 tawm ntawm 5 raws li nyob rau 1 neeg ntsuam xyuas
SKU: 797-63-7. Pawg: ,

AASraw yog nrog synthesis thiab muaj peev xwm ua tau los ntawm cov gram kom huab hwm coj ntawm Levonorgestrel hmoov (797-63-7), raws li CGMP kev tswj thiab kev tswj xyuas qhov system.

Levonorgestrel hmoov yog ib qho dawb crystalline hmoov hluavtaws progestational hormone, nws ua haujlwm los ntawm kev tiv thaiv tso tawm ntawm ib lub qe los ntawm lub zes qe menyuam lossis tiv thaiv fertilization ntawm lub qe los ntawm cov phev (cov txiv neej deev hlwb). Nws kuj tuaj yeem ua hauj lwm los ntawm kev hloov lub raj ntawm lub tsev menyuam (womb) los tiv thaiv kev xeeb tub. Levonorgestrel tau siv los tiv thaiv kev xeeb tub, Nws yog feem ntau yog siv rau hauv cov kua qaub (Norgestrel, 6533-00-2).

Hauj lwm yam khoom

Levonorgestrel hmoov yees duab


Levonorgestrel hmoov theem pib

Lub npe: Levonorgestrel hmoov
CAS: 797-63-7
Molecular Formula: C21H28O2
Molecular phaus: 312.45
txhais: 13-ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one ;13-ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one ;13-ethyl-17-hydroxy-19-dinor-17-alpha-pregn-4-en-20-yn-3-on(+)-1 ;17-alpha-ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one ;17-beta-hydroxy-18-methyl-19-nor-17-alpha-pregn-4-en-20-yn-3-one ;17-ethynyl-18-methyl-19-nortestosteron ;17-ethynyl-18-methyl-19-nortestosterone ;18-methyl-17-alpha-ethynyl-19-nortestosterone
Melt Point: 206 ° C
Kub Point: 459.1 ° C ntawm 760 mmHg
Flash Point: 195.4 ° C
Cia Temp: 2-8 ° C
xim: Dawb crystalline hmoov


Lus Tshaj Tawm Ntxiv. Raw Levonorgestrel hmoov kom paub

lub npe

Levonorgestrel hmoov

Levonorgestrel hmoov siv thiab dosing

1.Oral contraception:
Thaum noj tshuaj, Levonorgestrel hmoov yog siv hauv monophasicand triphasicformulations ntawm cov tshuaj kom sib tov ua ke, nrog cov kab mob uas muaj monophasic xws li 100-250μg, thiab triphasic koob tshuaj ntawm 50μg / 75μg / 125μg. Nws nrog cov estrogen ethinylestradiol hauv cov formulations.
Hauv tsawg heev txhua hnub ntawm 30μg, Levonorgestrel hmoov yog siv hauv ib co progestogen xwb pillformulations.

Kev tiv thaiv thaum muaj xwm txheej ceev

Levonorgestrel hmoov yog siv hauv cov tshuaj tiv thaiv kab mob thaum muaj xwm txheej (ECPs), ob qho tib si hauv Yuzpe txoj cai uas muaj cov tshuaj estrogen, thiab raws li Levonorgestrel nyoos hmoov nkaus xwb. Levonorgestrel hmoov-tsuas txoj kev siv Levonorgestrel nyoos hmoov 1.5 mg (raws li ib koob los yog ua ob zaug 0.75 mg koob 12 cov sijhawm sib nrauj) hauv 3 hnub ntawm kev sib deev uas tsis muaj kev tiv thaiv, nrog ib txoj kev tshawb fawb qhia tias pib thaum lig li 120 cov xuab moos (5 hnub) tom qab com yuav zoo.
Lub ntsiab mechanism ntawm Levonorgestrel nyoos hmoov li cov progestogen-tsuas yog thaum muaj xwm txheej tshuaj tiv thaiv kab mob yog, raws li International Federation of Gynecology thiab Obstetrics (FIGO), los tiv thaiv fertilization los ntawm inhibition ntawm ovulation thiab thickening ntawm ncauj tsev menyuam hnoos.FIGO tau teev tias: kev soj ntsuam ntawm cov pov thawj pom tias LNG [levonorgestreol] ECPs tsis tuaj yeem tiv thaiv implantation ntawm lub qe fertilized. Cov lus ntawm implantation yuav tsum tsis txhob muab tso rau hauv LNG ECP cov khoom cim npe. "Thaum Lub Kaum Ib Hlis 2013, European Medicines Agency (EMA) tau pom zoo hloov ntawm daim ntawv hais tias nws tsis tuaj yeem tiv thaiv ntawm lub qe fertilized. Lwm cov kev tshawb fawb tseem pom cov pov thawj los tsis paub meej. Thaum nws tsis pom zoo tias thaum muaj xwm txheej tiv thaiv kev kub ntxhov cuam tshuam rau implantation nws tsis tuaj yeem tsis cuam tshuam rau qhov tom qab muaj kabmob fertilization. Nyob rau lub Kaum Ib Hlis 2013, EMA kuj pom zoo hloov daim ntawv qhia rau HRA Pharma NorLevo hais tias: "Hauv kev soj ntsuam, kev siv tshuaj tiv thaiv tau raug txo rau cov poj niam uas hnyav 75 kg [165 pounds] lossis ntau tshaj, thiab Levonorgestrel hmoov tsis zoo rau cov poj niam uas muaj kev nyhav ntau tshaj 80 kg. "Thaum Lub Kaum Ib Hlis 2013 thiab Lub Ib Hlis 2014, FDA thiab EMA tau hais tias lawv tau xyuas seb qhov hnyav nce thiab lub cev qhov hnyav li cas (BMI) txo cov kev siv ntawm cov tshuaj tiv thaiv thaum muaj xwm ceev

Qhov tseem ceeb ntawm Levonorgestrel hmoov

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Ceeb toom rau Levonorgestrel hmoov

Levonorgestrel nyoos hmoov yog tib yam rau tag nrho cov kws tshuaj, qee cov teebmeem uas tsis pom kev tuaj yeem tshwm sim los ntawm kev siv Levonorgestrel hmoov. Yuav tsum nrog tus kws kho mob lossis tus kws kho mob tham nrog kev kho mob ua ntej siv. Feem ntau cov kev mob tshwm sim los ntawm kev noj 1.5 mg Levonorgestrel nyoos hmoov hauv cov kev sib tw (qhia los ntawm 10% lossis ntau tshaj) muaj xws li: ntuav, ua siab, kiv taub hau, mob taub hau, xeev siab, kev nyuab siab, pob txuv nce, txo HDL, tom qab ua haujlwm, kev mob kev nkeeg, kev mob qeeb, kev hnyav hnyav, hnyuv los ntshav, thiab qaug zog, amenorrhea. Mob siab thiab mob lub raum tsis zoo, lub mis hnyuv tau raug dai. cov kev mob tshwm sim ntau (qhia los ntawm 1% rau 10%) muaj raws plab, ntuav thiab mob hnyav heev; cov kev mob tshwm sim no feem ntau ploj hauv 48 cov xuab moos, nws ua tsis tau raws li cov tshuaj tiv thaiv kev noj tshuaj hauv lub cev, yuav tsum tau noj cov tshuaj tiv thaiv kab mob tom ntej. Cov poj niam uas haus luam yeeb yuav tsum tsis txhob noj (vim muaj teeb meem ntawm kab mob plawv).

Cov lus qhia ntxiv

Levonorgestrel hmoov (los yog l-norgestrel los yog D-norgestrel) yog lub cim thib ob hluavtaws progestogen, Nws yog kev tsim kho tsis haum hauv dej, soluble hauv chloroform, sparingly soluble ethanol thiab methylene chloride. Vim nws cov kev ua hauj lwm progestogenic, Levonorgestrel nyoos hmoov muaj antigonadotropic teebmeem, thiab muaj peev xwm suppress fertility thiab gonadal pw ua ke hormone ntau nyob rau hauv cov poj niam thiab cov txiv neej, nws ua rau inhibit ovulation los ntawm supressing gonadotrophin tawm ntawm lub pituitary caj pas. Qhov no tau nyob hauv suppressed qib follicle stimulating hormone (FSH) thiab luteinizing hormone (LH) nrog consequent inhibition of follicle txoj kev loj hlob thiab ovulation. Siv cov tshuaj ua muaj nyob hauv qee yam tshuaj hormonal contraceptives, nrog rau cov tshuaj noj hauv lub cev, cov tshuaj progestogen, cov tshuaj tiv thaiv thaum muaj xwm txheej, cov tshuaj tiv thaiv kab mob, cov tshuaj tiv thaiv kab mob, thiab cov tshuaj hormone hloov kho, tab sis tsis tuaj yeem tiv thaiv cov kab mob sib kis los ntawm kev sib deev. kuj hu ua D-norethindrone, sab laug Kanok ketone. Yog tias xav tau kev pom kev noj tshuaj, koj yuav tsum tau noj sai li sai tau hauv 72 cov sijhawm ua haujlwm, thiab zaum ob 12 tom qab. Cov tshuaj noj zoo dua qub sai sai tom qab uas lawv tau coj los tom qab sib deev.

Levonorgestrel nyoos hmoov

Min yuam 10grams.
Cov lus nug txog ntawm ntau npaum li cas (Hauv 1kg) tuaj yeem xa tawm hauv 12 teev tom qab them nyiaj.
Rau kev loj dua (Hauv 1kg) tuaj yeem xa tawm hauv 3 hnub ua hauj lwm tom qab them nyiaj.

Levonorgestrelraw hmoov muag

Kom muab rau yav tom ntej tom ntej.


Yuav ua li cas yuav Levonorgestrel hmoov los ntawm AASraw

1.To tiv tauj peb ntawm peb tus email nug qhov system, lossis hauv internettus sawv cev rau tus neeg sawv cev (CSR).
2.To muab peb nug koj qhov ntau thiab qhov chaw nyob.
3.Our CSR yuav muab nqe lus hais txog koj, qhov them nqi, tus lej nrhiav, kev xaib thiab kwv yees hnub uas tuaj txog (ETA).
4.Payment ua tiav thiab cov khoom xa tuaj rau 12 cov xuab moos (Rau kev txiav txim hauv 10kg).
5.Goods tau txais thiab muab tswv yim.

PRECAUTION THIAB DISCLAIMER:

Cov Khoom Siv No Yog Muag Rau Kev Tshawb Xyuas Siv Xwb. Cov ntsiab lus ntawm kev muag khoom Thov. Tsis Yog Rau Tib Neeg Noj, Tsis Kho Mob, Kho Tsiaj, lossis Tsev Neeg Siv.


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COA

COA 797-63-7 Levonorgestrel hmoov AASRAW

HNMR

Levonorgestrel hmoov (797-63-7) AASRAW HNMR

References & cov khoom citations

Levonorgestrel: Nws siv li cas, siv, kev phiv