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Lorcaserin HCL hmoov

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5.00 tawm ntawm 5 raws li nyob rau 1 neeg ntsuam xyuas
SKU: 1431697-94-7. Qeb:

AASraw yog nrog synthesis thiab muaj peev xwm ua tau los ntawm cov gram kom huab hwm coj ntawm Lorcaserin HCL hmoov (1431697-94-7), raws li CGMP kev tswj thiab kev tswj cov kev tswj qhov system.

Lorcaserin (1431697-94-7) HCL hmoov cuam ​​tshuam cov tshuaj tawm hauv lub hlwb uas tswj kev qab los noj mov. Lorcaserin HCL hmoov ua hauj lwm los ntawm kev pab kom koj tau noj cov zaub mov me me.Lorcaserin hydrochloride hmoov siv nrog rau kev noj haus thiab kev ua si kom kho rog. Lorcaserin hydrochloride hmoov yog siv los kho cov kab mob uas muaj feem xyuam rau ntshav qab zib, siab siab, lossis ntshav siab .

Hauj lwm yam khoom

Lorcaserin (1431697-94-7) video


Raw Lorcaserin (1431697-94-7) HCL cov hmoov av Basic Characters

Lub npe: Lorcaserin hydrochloride hmoov
CAS: 1431697-94-7
Molecular Formula: C11H15Cl2N
Molecular phaus: 232.1525
Melt Point: 212 ° C
Cia Temp: -20 ℃
xim: Dawb hmoov


Lorcaserin yog dab tsi

Lorcaserin (CAS 1431697-94-7), ua lag luam nyob rau hauv lub hom lag luam yog BELVIQ, qhov tseem ceeb yog Lorcaserin HCL hmoov 846589-98-8. Lub FDA tau pom zoo lorcaserin HCL rau cov neeg uas muaj rog (nrog lub cev huab hwm coj lub cev, los yog BMI, ntawm 30 lossis siab dua) lossis tus neeg rog (nrog rau BMI ntawm 27 lossis sab saum toj) thiab tseem muaj tsawg kawg ib qhov mob hnyav raws li Yam 2 mob ntshav qab zib, ntshav siab los yog mob siab.

Lorcaserin yog siv dab tsi

Lorcaserin HCL hmoov 846589-98-8, yog nyob rau hauv ib chav kawm ntawm cov tshuaj hu ua serotonin receptor agonists. Lorcaserin HCL yog siv nrog kev noj haus thiab lub cev tsim kho kom txhob muaj kev rog, rau kev mob ploj. Nws yog qee zaum muab los kho cov kab mob rog nrog roj (cholesterol), ntshav siab, lossis type2 diabetes. Tab sis Lorcaserin hydrochloride (Lorcaserin HCL) yuav tsis kho txhua yam mob lwm tus (xws li mob plawv, ntshav qab zib, ntshav siab).

Lorcaserin mechanism ntawm kev txiav txim

Lorcaserin hydrochloride hmoov ua hauj lwm los ntawm kev tswj kev noj qab haus huv - uas yog qhib lub hlwb receptors rau serotonin, ib tug neurotransmitter uas ua txoj kev xav ntawm satiety thiab siab. Txaus ntawm cov zaub mov yog tswj los ntawm satiety center, nyob rau hauv ventromedial nucleus ntawm hypothalamus thiab kev tshaib plab centre present rau lateral hypothalamus. Muaj ntau txoj hauv kev los ntawm cov chaw siab dua thiab txoj hnyuv hauv plab hauv txuam nrog cov keeb kwm nucleus, uas muaj ob hom kev tswj neurons tswj zaub mov noj. Ua ntej, cov khoom noj khoom haus ua kom tau txais cov khoom noj uas ua rau cov ntsev uas muaj ntsig txog lub cev thiab cov neuropeptide Y; thiab ob, cov khoom noj khoom haus ua kom tsis muaj teeb meem pab pawg neeg uas muaj cocaine thiab amphetamine tswj cov ntawv sau (CART) thiab pro-opiomelanocortin (POMC) neurons. POMC muaj 5-HT 2C receptors, uas yog thaum tso qhib tawm alpha-melanocyte-stimulating hormone (alfa-MSH) .Both inhibitory thiab stimulatory neurons ntxiv tej yaam num paraventricular nucleus hauv hypothalamus.Paraventricular nucleus muaj melanocyte 4 receptors (MC4R) uas inhibits appetiteNas kho koob tshuaj lorcaserin ua raws li 5-HT 2C agonist ntawm POMC neurons, uas yog tshwm sim ua rau kev tso tawm ntawm alpha MSH. Ntxiv alpha MSH ua rau MC4R hauv paraventricular nucleus hauv hypothalamus, ua rau kom txo tau qhov qab los noj mov. Hauv supratherapeutic koob, lorcaserin kuj ua rau 5-HT 2B thiab 5-HT 2A receptors.

Yuav ua li cas siv Lorcaserin HCL hmoov (CAS 1431697-94-7)

Lorcaserin HCL hmoov yog ib tug dawb dawb rau cov hmoov dawb uas muaj cov kua dej ntau dua 400 mg / mL. Txhua BELVIQ XR ntsiav tshuaj muaj 20.8 mg ntawm crystalline lorcaserin hydrochloride hemihydrate, sib npaug XMUMX mg lorcaserin hydrochloride hmoov, thiab cov khoom xyaw nram qab no: microcrystalline cellulose NF; mannitol USP; hypromellose 20.0 USP; ethylcellulose dispersion Hom B NF; hypromellose 2208 USP; colloidal silicon dioxide NF; polyvinyl cawv USP; polyethylene glycol NF; titanium dioxide USP; talc USP; FD & C daj # 2910 / hnub poob daj FCF; pas dej txhuas txhuas; hlau oxide daj NF; hlau oxide liab NF; thiab magnesium stearate NF.

Lorcaserin HCL hmoov 846589-98-8 los ntawm daim ntawv xaj thiab tau noj 1-2 zaug ib hnub, nrog lossis tsis noj mov. Lorcaserin yuav tsum siv nrog rau txo cov khoom noj roj tsawg thiab ib qho kev npaj ua si.

Kev sib tsham Lorcaserin

-monemonine oxidase inhibitors xws li isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), selegiline (Emsam, Eldepryl, Zelapar), rasagiline (Azilect)

-Selotonin reuptake inhibitors (SSRIs) xws li escitalopram (Lexapro), sertraline (Zoloft), citalopram (Celexa), paroxetine (Paxil), fluoxetine (Prozac, Sarafem), thiab fluvoxamine (Luvox)

-cais dej tshuaj tiv thaiv xws li trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), thiab clomipramine (Anafranil)


Yuav ua li cas yuav Lorcaserin HCL hmoov (CAS 1431697-94-7) los ntawm AASraw

1.To tiv tauj peb ntawm peb tus email nug qhov system, lossis hauv internettus sawv cev rau tus neeg sawv cev (CSR).
2.To muab peb nug koj qhov ntau thiab qhov chaw nyob.
3.Our CSR yuav muab nqe lus hais txog koj, qhov them nqi, tus lej nrhiav, kev xaib thiab kwv yees hnub uas tuaj txog (ETA).
4.Payment ua tiav thiab cov khoom xa tuaj rau 12 cov xuab moos (Rau kev txiav txim hauv 10kg).
5.Goods tau txais thiab muab tswv yim.


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COA

COA 1431697-94-7 Lorcaserin HCL hmoov AASraw

HNMR

Raw Synephrine HCL hmoov (5985-28-4) hplc = 98% | AASraw lwm tus neeg

Zaub mov txawv

References & cov khoom citations

20 tseem ceeb tshaj plaws Koj yuav tsum paub txog Lorcaserin HCL hmoov