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N-Boc-dolaproine (120205-50-7)

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5.00 tawm ntawm 5 raws li nyob rau 1 neeg ntsuam xyuas
SKU: 120205-50-7. Qeb:

AASraw yog nrog synthesis thiab muaj peev xwm ua tau los ntawm cov gram kom loj txog kev txiav txim siab ntawm N-Boc-dolaproine (CAS 120205-50-7), raws li CGMP kev tswj thiab kev tswj xyuas qhov kev tswj kom zoo.

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N-Boc-dolaproine (120205-50-7) yees duab


N-Boc-dolaproine (120205-50-7) tus cwj pwm yooj yim

Lub npe: N-Boc-dolaproine
CAS: 120205-50-7
Molecular Formula: C14H25NO5
Molecular phaus: 287.352
Melt Point: 182 ° C (dec.)
Cia Temp: 4 ° C, cia tom qab nitrogen
xim: Dawb


N-Boc-dolaproine (CAS 120205-50-7) siv nyob rau hauv steriods kho

npe

Product Name:(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)- 3-methoxy-2-methylpropanoic acid, (2R,3R)-BOC-dolaproine
(2R, 3R) - 3 - ((S) -1- (tertbutoxycarbonyl) pyrrolidin-2-yl) -3-Methoxy-2-Methylpropanoic acid; Dolproline; N-Boc-dolaproline; (2R, 3R) (120205R, 50R) -7 - ((S) -2- (tert-butoxycarbonyl) pyrrolidin-3-yl) -3-Methoxy- (X-xxm-dolaproine) N-Boc-dolaproine (CAS 1-2-3) N-Boc-Dolaproline acid (K ntsev) (N-Boc-DAP-K ntsev) (dawb acid)

N-Boc-dolaproine (CAS 120205-50-7) Siv

(2R, 3R) -BOC-dolaproine yog ib qho β-methoxy-γ-amino acid tivthaiv dolastatin 10, ib tug neeg saib xyuas antineoplastic.

3. Ceeb toom rau N-Boc-dolaproine
Rau kev tshawb fawb siv xwb

4.Xaiv cov lus qhia:
Ib qho yooj yim thiab stereoselective synthesis ntawm N-Boc-dolaproine ntawm Baylis-Hillman cov tshuaj tiv thaiv
Hauv kev sib txuas lus no peb tau tshaj tawm txog kev sib txuas ntawm N-Boc-dolaproine (CAS 120205-50-7) (Dap), ib qho amino acid residue ntawm antineoplastic pentapeptide Dolastatin 10. Peb lub tswv yim raws li Baylis-Hillman cov tshuaj tiv thaiv ntawm N-Boc-prolinal thiab methyl acrylate, ua raws li ib diastereoselective coj nyiaj hydrogenation thiab hydrolysis ntawm cov kev ua ester.

Ib qho yooj yim thiab thev naus laus zis mus rau tag nrho cov synthesis ntawm N-Boc-dolaproine. Tus synthesis yog ua raws li kev siv tau ntawm Baylis-Hillman cov tshuaj tiv thaiv thiab tau ua tiav nyob rau hauv plaub cov kauj ruam nrog tag nrho cov paib ntawm 27%.


Yuav ua li cas yuav N-Boc-dolaproine ntawm AASraw

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