Baet Pregabalin hmoov Chaw tsim tshuaj paus
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Pregabalin hmoov

Rating: SKU: 148553-50-8. Qeb:

AASraw yog cov chaw tsim khoom ntawm Pregabalin hmoov uas muaj kev ywj pheej lab thiab lub Hoobkas loj raws li kev txhawb nqa, tag nrho cov khoom tsim tawm yuav ua raws li CGMP kev tswj hwm thiab kev tswj xyuas qhov zoo. Cov khoom siv tau ruaj khov, ob qho tib si khw muag khoom thiab muag khoom xaj tau txais.

Hais nrawm

Hauj lwm yam khoom

 

Pregabalin hmoov yees duab

 

 


 

Cov Cim Cim

Khoom npe: Pregabalin hmoov
CAS nr: 148553-50-8
Molecular Formula: C8H17NO2
Molecular phaus: 159.23
Melt Point: 194-196 ° C
xim: Dawb los yog tawm dawb crystal hmoov
Cia Temp: RT

Pregabalin hmoov tshuaj xyuas

Pregabalin hmoov yog hmoov dawb uas siv los ua tshuaj tiv thaiv kab mob vwm, tseem hu ua anticonvulsant. Nws ua haujlwm los ntawm kev ua kom qeeb impulses hauv lub hlwb uas ua rau qaug dab peg. Pregabalin hmoov kuj tseem cuam tshuam cov tshuaj hauv lub hlwb uas xa cov cim mob thoob plaws hauv lub paj hlwb.

Pregabalin hmoov yog siv los kho qhov mob los ntawm fibromyalgia, lossis mob paj hlwb hauv cov neeg mob ntshav qab zib (diabetic neuropathy), herpes zoster (post-herpetic neuralgia), lossis kev raug mob qaum qaum.

Pregabalin hmoov kuj tseem siv nrog lwm cov tshuaj los kho qhov pib qaug dab peg ib nrab ntawm cov neeg laus thiab cov menyuam yaus uas muaj hnub nyoog tsawg kawg yog 1 lub hlis.Pregabalin nyoos hmoov kuj tseem siv tau rau cov hom phiaj uas tsis tau teev tseg hauv phau ntawv qhia tshuaj no.

 

Pregabalin Mechanism ntawm Kev Ua

Pregabalin yog ib qho tshuaj anticonvulsant siv los kho cov mob neuropathic mob thiab fibromyalgia, thiab rau kev kho mob ntawm qee qhov pib qaug dab peg nrog rau lwm cov tshuaj tiv thaiv.

Txawm hais tias cov txheej txheem ntawm kev txiav txim tsis tau piav qhia tag nrho, cov kev tshawb fawb uas muaj feem cuam tshuam nrog cov tshuaj qhia tias presynaptic binding ntawm pregabalin rau voltage-gated calcium channels yog qhov tseem ceeb rau cov tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob pom hauv cov qauv tsiaj.

Los ntawm kev khi presynaptically rau alpha2-delta subunit ntawm voltage-gated calcium channels nyob rau hauv lub hauv paus paj hlwb, pregabalin modulates tso tawm ntau excitatory neurotransmitters nrog rau glutamate, tshuaj-P, norepinephrine, thiab calcitonin noob ntsig txog peptide. alpha2-delta subunit los ntawm kev lag luam los ntawm dorsal cag ganglia mus rau tus txha caj qaum dorsal horn, uas kuj tseem tuaj yeem pab txhawb rau kev ua haujlwm. Txawm hais tias pregabalin yog cov txheej txheem derivative ntawm inhibitory neurotransmitter gamma-aminobutyric acid (GABA), nws tsis khi ncaj qha rau GABA lossis benzodiazepine receptors.

 

Kev siv / Daim ntawv thov ntawm Pregabalin

❶ Pharmacological kev ua tau zoo: Pregabalin yog ib qho tshiabγ-aminobutyric acid (GABA) receptor agonist, tuaj yeem thaiv qhov voltage-dependent calcium channels kom txo tau cov neurotransmitter tso tawm.

❷ Lub chaw kho mob tseem ceeb rau kev kho mob peripheral neuropathic mob nrog rau ib feem ntawm kev kho mob ntawm focal qaug dab peg.

❸ Kev kho mob qaug dab peg hauv kev txhim kho cov tshuaj muaj txiaj ntsig zoo tshaj plaws hauv kev kho tshuaj zoo dua thiab kev tswj hwm yooj yim dua. Nws kuj tseem siv tau los kho qhov mob thiab kev ntxhov siab.

 

Cov teebmeem ntawm Pregabalin

Zoo li feem ntau cov tshuaj, Lyrica tuaj yeem ua rau mob me lossis mob hnyav. Qhov no tsis yog tag nrho cov kev mob tshwm sim thiab lwm yam yuav tshwm sim. Ib tus kws kho mob tuaj yeem qhia koj txog kev mob tshwm sim. Yog tias koj ntsib lwm yam teebmeem, tiv tauj koj tus kws muag tshuaj lossis tus kws kho mob.

 

Feem Xyuam Los Feem

Koj tuaj yeem ntsib kev phiv thaum noj pregabalin. Cov kev phiv tshwm sim ntawm pregabalin muaj xws li:

▪ kiv taub hau

▪ qaug zog

▪ kev tsis meej pem

▪ pom qhov muag tsis pom kev

▪ tshee tshee

▪ tsis khov thaum taug kev

▪ hnyav nce

▪ cem quav

▪ Qhov ncauj qhuav.

 

Mob hnyav heev

Hu rau koj tus kws kho mob tam sim yog tias koj muaj kev phiv loj heev. Hu rau 911 yog tias koj cov tsos mob xav tias muaj kev hem thawj rau lub neej lossis yog tias koj xav tias koj muaj xwm txheej ceev. Cov kev mob tshwm sim hnyav thiab lawv cov tsos mob tuaj yeem suav nrog cov hauv qab no:

▪ Kev xav tua tus kheej lossis sim tua tus kheej: Cov tsos mob yuav suav nrog kev sim tua tus kheej, tshiab lossis ua rau muaj kev ntxhov siab lossis kev nyuaj siab, teeb meem pw tsaug zog, ntxhov siab, ua rau muaj kev phom sij txaus ntshai, thiab kev hloov pauv ntawm lub siab lossis tus cwj pwm.

▪ Kev ua xua hnyav: Cov tsos mob yuav muaj xws li ua pa nyuaj, khaus khaus, thiab o ntawm tus nplaig, daim di ncauj, qhov ncauj, lossis caj pas.

▪ Teeb meem plawv

▪ Teeb meem ua pa hnyav

Qee qhov kev mob tshwm sim tuaj yeem ua tau zoo dua nyob rau lub sijhawm, thaum lwm tus xws li kiv taub hau thiab tsaug zog yuav kav ntev npaum li koj noj tshuaj.

 

Pregabalin Cia

Tib neeg yuav tsum khaws cov tshuaj no ntawm chav tsev kub tswj, txog 68 degrees txog 77 degrees Fahrenheit.

Yog tias mus ncig, nco ntsoov nqa koj cov tshuaj nrog koj thiab khaws lub raj mis lossis lub thawv rau hauv koj lub hnab nqa. Tsis txhob tso cov tshuaj no rau hauv koj lub tsheb, tshwj xeeb tshaj yog nyob rau hauv qhov txias heev los yog kub kub.

 

Phau Ntawv Qhia Yuav Pregabalin Powder los ntawm AASraw kauj ruam yog kauj ruam

♦ Mus saib AAS lub vev xaib, xaiv cov hmoov pregabalin uas koj xav tau, thiab tso koj qhov kev sib cuag thiab cov lus ntawm AAS wbsite, tom qab ntawd xa, AAS Cov Kev Pabcuam Cov Neeg Siv Khoom yuav teb koj hauv 12 teev ib zaug tau txais koj cov lus, tom qab ntawd tham hauv cov ntsiab lus.

♦ Tsuas yog xa email lossis xa cov lus ntawm whatsapp rau cov neeg ua haujlwm hauv AAS thiab qhia rau lawv tias koj xav yuav pregabalin hmoov los ntawm aasraw, tom qab ntawd tham kom meej, txog qhov purity, kom muaj nuj nqis, Shipping, chaw nyob, xaiv cov kev them nqi tsim nyog, cov khoom tuaj yeem ua tau. xa tawm tsis pub dhau 12 teev tom qab them nyiaj, tom qab them nyiaj, koj yuav tau txais tus lej taug qab, kuj AAS cov neeg siv khoom yuav ua rau koj hloov kho raws sijhawm, tom qab ntawd koj tsuas yog yuav tsum tau zaum yooj yim, tos koj pob.

♦ AAS yog ib lub tuam txhab nyob hauv Suav teb, Kev nyab xeeb, yog tias koj muaj phooj ywg nyob hauv Suav teb, koj tuaj yeem cia koj cov phooj ywg tuaj xyuas lawv lub tuam txhab, tham kom meej, thiab tau txais cov khoom koj xav tau.

 

reference

[1] Dworkin RH, O'Connor AB, Backonja M, et al. Pharmacological kev tswj ntawm qhov mob neuropathic: pov thawj-raws li cov lus pom zoo. Mob 2007; 132:237-51.

[2] Finnerup NB, Jensen TS. Kev kho mob siv pregabalin hauv kev tswj cov mob hauv nruab nrab neuropathic. Neuropsychiatric Disease and Treatment 2007; 3:885-91.

[3] Kalso E, Aldington DJ, Moore RA. Cov tshuaj rau mob neuropathic. BMJ 2013; 347:f7339.

[4] Mannix, Liam (December 18, 2018). “Cov tshuaj nrov no txuas nrog kev quav tshuaj thiab tua tus kheej. Vim li cas cov kws kho mob pheej muab tshuaj rau nws?”. Lub sijhawm Canberra. Muab lo rau Lub Kaum Ob Hlis 18, 2018.

[5] Txawm li cas los xij, James W. Willmore, James; Brumback, Roger A. (2009). Advanced Therapy hauv Epilepsy. PMPH-USA. p. 302. ISBN 978-1-60795-004-2 ib.